ʻO Casein phosphopeptides (CPP) kahi ʻano mea hoʻohui meaʻai hana
ʻO Casein phosphopeptide ka casein hydrolyzed e trypsin a i ʻole trypsin, i hoʻomaʻemaʻe ʻia a hoʻomaʻemaʻe ʻia. ʻO kona ʻano kumu ʻo Ser (P) - Ser (P) - Ser (P) - Glu Glu - (Ser: serine, Glu: glutamic acid, P: phosphate). Aia nā koena phosphoserine (- Ser (P) -) i loko o kēia ʻano i loko o nā pūʻulu a lawe i nā koina maikaʻi ʻole i ka pH alkaline nāwaliwali o ka ʻōpū, hiki ke pale i ka hana hou aʻe o nā enzyme digestive a pale i ka CPP mai ka hydrolysis hou aʻe, e hopena i ka noho paʻa. i loko o ka ʻōpū. Ua ʻike ka noiʻi kūloko ʻo ka liʻiliʻi o ka ratio molar o ka nitrogen i ka phosphorus i CPP, ʻoi aku ka pōkole o ke kaulahao peptide o CPP, a ʻoi aku ka kiʻekiʻe o ka puʻupuʻu o nā pūʻulu phosphate, e hopena i ka maʻemaʻe CPP kiʻekiʻe a me ka hoʻoikaika ikaika ʻana i ka absorption calcium a me ka hoʻohana ʻana.
He maʻalahi ke komo ʻana o ka calcium i ka wā e noho ai ma ke ʻano o nā ion, a ma nā wahi kūʻokoʻa a nāwaliwali ka alkaline, ua maʻalahi ke hana ʻana i nā paʻakai hiki ʻole ke hoʻoheheʻe me nā ion acid a nalowale. Hōʻike ʻia ka hopena absorption o ka CPP ma ka calcium e kona hiki ke hoʻopaʻa me ka calcium i nā wahi kūʻokoʻa a me ka nāwaliwali alkaline, kaohi i ka hoʻokumu ʻana o nā insoluble precipitates, pale i ka nalowale o ka calcium, a i ka hopena passively e hoʻopili ma muli o ka piʻi ʻana o ka ʻike calcium manuahi. Hōʻike ka noiʻi o kēia manawa i ka hopena o ka CPP i ka hoʻoikaika ʻana i ka absorption calcium i hōʻike nui ʻia ma nā ʻano aʻe:
- (1) Hoʻoikaika i ka absorption o ka calcium i loko o ka ʻōpū liʻiliʻi.
ʻO nā meaʻai cereal i loko o ka meaʻai kanaka ka nui o nā mea phosphorus kiʻekiʻe e like me ka phytic acid a me ka inositol hexaphosphate, e hui pū me ka calcium i ka pH 7-8 environment ma ka ʻaoʻao haʻahaʻa o ka ʻōpū liʻiliʻi e hana i ka calcium phosphate precipitates. Hiki i ka CPP ke pale i ka hoʻokumu ʻana o ka ua o ka calcium phosphate, mālama i kahi kiʻekiʻe o ka calcium manuahi, hoʻoikaika i ka absorption passive o ka calcium, a lilo i ala ʻē aʻe no ka huaʻa D ma ke ʻano he mea hoʻolaha hoʻoulu calcium.
- (2) Hoʻoikaika i ka hoʻohana ʻana i ka calcium e nā iwi.
Hōʻike nā hoʻokolohua holoholona e hiki i ka CPP ke hoʻoikaika i ka absorption a me ka hoʻohana ʻana i ka calcium, hoʻonāwaliwali i ka hopena o ka osteoclast a kāohi i ka resorption iwi.
- (3) Hoʻoikaika i ka hoʻohana ʻana i ka calcium e nā niho.
I ka wā ma mua, ua manaʻo ʻia ʻo ka nau ʻana i ka paʻakai ma hope o ka ʻai ʻana e hiki ke hoʻoulu i ka huna ʻana o ka kohu, e ʻae ana i ka saliva alkaline e hoʻopaʻa i nā mea ʻakika ma ka plaque niho mai ka ʻino ʻana i ka enamel, e kōkua ana i ka pale ʻana i ka puka ʻana o nā caries niho. I nā makahiki i hala iho nei, ua ʻike ʻia ka noiʻi hiki i ka CPP i loko o ka cheese ke hoʻopaʻa i nā ion calcium i loko o ka meaʻai i nā caries niho, e hōʻemi ana i ka enamel demineralization, a pēlā e hoʻokō ai i nā pahuhopu anti caries.
Ua ʻike ʻia ka noiʻi ʻana ʻoi aku ka kiʻekiʻe o ka sperm i loko o ka moʻomeheu i loaʻa i ka CPP i ke komo ʻana i nā pūnaewele hua manu a hiki ke hōʻemi i ke kiʻekiʻe o ka hoʻololi ʻana o ka sperm, e ʻoi aku ka paʻa o ka ulu ʻana o ka embryonic. Hiki i ka CPP ke hoʻomaikaʻi i ka bioavailability o nā ion metala e like me ka hao, zinc, a me ka magnesium, no laila ua ʻike ʻia ʻo ia he mea peptide me ka hana lawe metala. I kēia manawa, ua hoʻohana ʻia ka CPP i ka laiki curry a nā keiki, nā mea inu, nā ʻōpala a me nā meaʻai a me nā huahana olakino ma waho. Ke hoʻomau nei ka noiʻi a me ka noi ʻana i ka mālama ʻana i ka nele o ka calcium i nā keiki, ka osteoporosis i ka poʻe ʻelemakule, ka infertility, a me ke olakino niho. No ka mea he peptide ʻo CPP i lawe ʻia mai nā protein kūlohelohe a loaʻa nā pōmaikaʻi o ka liʻiliʻi o nā hopena ʻino, palekana, a me ka hilinaʻi, e hoʻohana nui ʻia. Ua aʻo ʻia ka sensitization reaction o casein, skim milk protein a me CPP i nā ʻāina ʻē, a ua ʻike ʻia he liʻiliʻi loa ka sensitization o CPP, e hōʻike ana e hiki ke hoʻopili ʻia i ke kumukānāwai maʻi i ka waiū. Eia nō naʻe, pono e hoʻomaopopo ʻia he paʻakikī loa nā mea e pili ana i ka hopena o ka CPP, a pono e hoʻomaikaʻi ʻia kā lākou kuleana i ka metabolism calcium.
Ka manawa hoʻouna: Iune-15-2023
