I ka wā e pili ana i ke olakino a me ka maikaʻi, ʻo ka loaʻa ʻana o nā mea hoʻopihapiha kūpono hiki ke hana i kahi honua o ka ʻokoʻa. E haʻi ana ʻo Keira iā ʻoe e pili ana i ka resveratrol ma kēia pou i kēia lā. Kaulana ʻo Resveratrol i ka honua ma muli o kahi French Paradox i kūkākūkā ʻia i ka makahiki 1990, i ka wā i manaʻo ʻia ʻo ke kumu o ka poʻe Farani e ʻai ai i ka mea momona momona ʻaʻole i maʻi i ka maʻi cardiovascular no ka mea aia ka resveratrol i loko o ka waina ʻulaʻula a lākou e inu pinepine ai. .
Mai ia manawa, ua hoʻomau ʻia ka ʻike ʻia ʻana o ka resveratrol no kāna mau pono olakino e pili ana i ka antioxidant, anti-inflammatory, anticancer, a me nā hopena pale cardiovascular.
He aha ka resveratrol?
Resveratrol, he polyphenol organic compound non-flavonoid, he antitoxin i hanaia e na mea kanu he nui ke hooulu ia, me ke ano kemika C14H12O3. I ka makahiki 1940, ua hoʻokaʻawale mua ke kanaka ʻepekema Kepani ʻo MichioTakaoka i ka resveratrol mai Veratrum album ma ka ʻohana lilia, a ma hope ua loaʻa mai ia mai Polygonum cuspidatum i ka ʻohana polygonum ma 1963. Hiki ke hoʻohui ʻia i loko o nā lau waina a me nā ʻili hua waina a he mea bioactive i loko o ka waina a wai hua waina. Hoʻopili maʻalahi ia e ka waha a hoʻokuʻu ʻia i loko o ka mimi a me ka stool ma hope o ka metabolism. Ua hōʻike ʻia nā hoʻokolohua in vitro a me nā holoholona i ka resveratrol he antioxidant, anti-inflammatory, anticancer a me nā hopena pale cardiovascular.
Resveratrolua laha nui ia ma na mea kanu, a ma ka makahiki 2021, ua loaa ma mua o 70 mea kanu mai 21 ohana, I ka mea, i loaʻa ma Vitis, Ampelopsis, Polygonum, Arachis, Cassia, Sophora, Veratrum, Veratrum a me Eucalyptus. ʻO nā mea kanu maʻamau i loaʻa i ka resveratrol nā hua waina, knotweed, peanuts, cassia, a me nā mea ʻē aʻe. ʻoi aku ka lōʻihi ma muli o ka unuhi ʻana a me ka hoʻokaʻawale ʻana mai nā mea kanu. ʻO ke kaʻina hana synthesis o resveratrol e hoʻohana nui i ka pane Wittig e ʻike i ka splicing o ʻelua mau apo benzene, a hiki i ka hua ke piʻi ma mua o 50%.
He aha nā hopena o ka resveratrol?
- Kūʻē i ka ʻelemakule
I nā makahiki i hala iho nei, ua ʻike ʻia ʻo ka hapa nui o nā polyphenols he koʻikoʻi anti-oxidation a me nā hopena radical anti-free.
Ma keʻano he antioxidant kūlohelohe, he ikaika ka resveratrol i ka hoʻopau ʻana iā ia iho a me ka anti-lipid peroxidation, a ua hoʻohālikelike ʻia me nā antioxidants kuʻuna e like me ka vitamina C, butylhydroxytoluene, tocopherol, resveratrol he hopena antioxidant ʻoi aku ka maikaʻi.
ResveratrolHoʻohana ʻo ia i kāna hopena antioxidant ma o ka scavenging a i ʻole ke kāohi ʻana i nā radical manuahi, ke kāohi ʻana i ka lipid peroxidation, ka hoʻoponopono ʻana i ka hana o nā enzymes pili i ka antioxidation a me nā hana ʻē aʻe.
Kūʻē ʻo Resveratrol i ka ʻelemakule ma muli o ka lipid peroxidation i hana ʻia e nā radical manuahi a me kā lākou metabolites. I ka manawa like, hoʻoneʻe ʻo resveratrol i nā radical manuahi, hoʻemi i ka ʻike o ka H₂O₂ i ka ʻili, hoʻomaikaʻi i ka hana o ATPase, a pēlā ka hopena o ka hoʻopaneʻe ʻana i ka ʻelemakule.
- E hoʻomalu i ke kō koko
ʻO ka maʻi diabetes ka maʻi maʻamau maʻamau, akā ʻoi aku ka maʻalahi o ka pale ʻana, akā no kēia mea e ʻae pinepine ka poʻe i ka maʻalahi, ʻo ka pilikia o ka maʻi diabetes, ʻo ia ka arteriosclerosis, me ka hoʻonui nui ʻana i ka nui o ka myocardial infarction, stroke, inā ʻo ia. pili i nā microvessels kīkī, e hoʻopōʻino hou aʻe i ke kīpē, no laila he mea nui ka mālama ʻana i ke kō koko i ke ola.
Ma kahi haʻawina liʻiliʻi, ua hoʻomaikaʻi ʻo resveratrol (150 mg i kēlā me kēia lā no 30 mau lā, kahi DSM proprietary component resVida) i hoʻomaikaʻi i ke kiʻekiʻe o ke kō koko (e 4.2%) a me nā pae insulin (e 13.7%) i ka poʻe paona.
- Anti-tumor, anti-cancer
He hopena koʻikoʻi ka Resveratrol i ka maʻi hepatocellular carcinoma, ka maʻi maʻi umauma, ka maʻi maʻi ʻāʻī, ka maʻi ʻōpū, ka maʻi leukemia a me nā mea ʻē aʻe. Ua hōʻoia ʻia kekahi poʻe loea e loaʻa i ka resveratrol ka hopena paʻa ʻole i nā cell melanoma ma ke ʻano MTT a me ka cytometry kahe.
Ua hōʻike ʻia e hiki i ka resveratrol ke hoʻoikaika i ka lāʻau lapaʻau maʻi kanesa, pāʻani i ka hopena "1+1>2", a keʻakeʻa pono i ka hana o nā pūnaewele maʻi maʻi. Akā i kēia manawa, ma muli o ka paʻakikī o ka hana anti-tumor o ka resveratrol, ʻaʻole i hiki i nā mea noiʻi ke ʻae i ka manaʻo o kāna hana.
- Nā hana ʻē aʻe
Loaʻa iā Resveratrol ka antibacterial, antioxidant, immunomodulatory, antiasthmatic a me nā hana olaola ʻē aʻe. ʻImi nui ʻia ʻo Resveratrol ma muli o kāna mau hana olaola like ʻole.
Pehea e wehe ai i ka resveratrol?
- ʻO ke ʻano unuhi mea kanu maoli
Ua lawe ʻia ʻo Resveratrol a hoʻomaʻemaʻe ʻia mai ka hua waina, knotweed a me ka pī. Hoʻohana nui ʻia ka ʻenehana hoʻoheheʻe crude i ke ʻano o ka hoʻoheheʻe ʻana i ka mea hoʻoheheʻe organik, ke ʻano hoʻoheheʻe alkali a me ke ʻano o ka hoʻoheheʻe ʻana i ka enzyme, ke ʻano hoʻoheheʻe i kōkua ʻia i ka microwave, CO2 supercritical extraction, ultrasonic assisted extraction a me nā ʻano hana hou ʻē aʻe. ʻO ke kumu nui o ka hoʻomaʻemaʻe ʻana ʻo ia ka hoʻokaʻawale ʻana i ka resveratrol cis, trans isomer a me resveratrol Xib mai ka resveratrol maka i unuhi ʻia e loaʻa ai ka trans-resveratrol. ʻO nā ʻano hoʻomaʻemaʻe maʻamau ʻo ia ka chromatography, silica gel column chromatography, thin layer chromatography, high performance liquid chromatography a pēlā aku.
- ʻO ke ʻano hana synthesis
Ma muli o ka haʻahaʻa haʻahaʻa o ka resveratrol i loko o nā mea kanu a me ke kumukūʻai kiʻekiʻe o ka unuhi ʻana, ua lilo ka hoʻohana ʻana i nā ʻano kemika, biological a me genetic engineering no ka loaʻa ʻana o ka resveratrol i mea nui i ke kaʻina hana. ʻO ka pane ʻana o Perkin, ka pane Hech a me ka pane ʻana o Witting-Hormer he mau ʻano kemika oʻo no ka synthesis o resveratrol, me ka hua o 55.2%, 70% a me 35.7%, kēlā me kēia. Ke hoʻohana nei i ka ʻenehana ʻenekinia e hoʻomalu a hoʻomaikaʻi paha i ke ala biosynthesis o resveratrol no ka loaʻa ʻana o nā laina mea kanu kiʻekiʻe; Ua hoʻonui ʻia ka hua o ka resveratrol e 1.5 ~ 3.0 mau manawa e ka mutagenesis a me nā ʻano hana ʻē aʻe.
He hui kūikawā ʻo Aogubio i ka hana ʻana a me ka hāʻawi ʻana i nā mea lāʻau pharmacologically active, nā mea maka a me nā mea kanu mea kanu, me nā nutraceuticals no ka hana ʻana i nā mea hoʻohui kanaka. Kūleʻa mākou i nā lāʻau lapaʻau a me nā huahana no ka lāʻau lapaʻau, meaʻai, nutraceutical a me nā ʻoihana hoʻonaninani, a ke kūpaʻa nei mākou i ka hāʻawi ʻana i nā mea kūʻai aku i nā mea hoʻohui kiʻekiʻe a maikaʻi.
KA HOʻOMAʻI O KA MANAʻO:
Hoʻolako ʻia kā mākou hale me kahi keʻena e hoʻohana ana i ka chromatography kinoea hou e hoʻāʻo ikaika i ka maʻemaʻe a me ka ikaika o kā mākou mau mea maka; e hōʻoia i ka loaʻa ʻana o kā mākou mea kūʻai i nā huahana maikaʻi loa i nā manawa āpau.
LAWELAWE MEA KŪʻAI MAI:
Ke mālama nei i kā mākou pahuhopu o ka hoʻokō ʻana i kahi Kulekele Hoʻohanohano Satisfaction, ua mākaukau mau kā mākou hui hoʻolaʻa e hāʻawi i kēlā me kēia o kā mākou mea kūʻai aku me ka ʻoihana alakaʻi i nā mea kūʻai aku ma kēlā me kēia ʻano o ke kauoha.
Inā makemake ʻoe e ʻike e pili ana a kūʻai paha i ka resveratrol kiʻekiʻe, e ʻoluʻolu e kelepona me kayla.
Hoʻokaʻaʻike: Keira Zhang
Leka uila: sales06@aogubio.com
Kelepona: +86 18066856327
Ka manawa hoʻouna: Jan-08-2024
