He aha ka Benfotiamine?

1. ʻO ka neuropathy diabetic

ʻIke ʻia ka lāʻau ʻo Benfotiamine i kahi hoʻolālā kūpono no ka pale ʻana i ka nephropathy diabetic, kahi hoʻopiʻi koʻikoʻi o ka maʻi maʻi diabetes, e pili ana i kahi pilikia nui o ka maʻi puʻuwai a me ka make. ʻO ka nui o ka glucose kiʻekiʻe e alakaʻi i ka hōʻiliʻili o nā triosephosphates; alakaʻi kēia i ka biochemical dysfunction a ma hope o ka ulu ʻana o ka nephropathy maʻi maʻi.

Ua hōʻike ʻia nā haʻawina preclinical i nā ʻiole e pale aku ka benfotiamine i ka hōʻiliʻili ʻana o nā triosephosphates i ka maʻi diabetes a no laila ke keʻakeʻa nei i ka ulu ʻana o ka nephropathy.

2. Hoʻomaikaʻi i ka naʻau i ka maʻi o Alzheimer

Ua hōʻike ʻia nā haʻawina preclinical e hāʻawi ka benfotiamine i nā hopena maikaʻi i ka hōʻino cognitive i ka maʻi o Alzheimer. Ua hōʻike ʻia ʻo Benfotiamine e hōʻemi i ka waiho ʻana o ka amyloid i nā ʻano holoholona o ka maʻi o Alzheimer. Eia naʻe, ʻaʻole i hōʻike ʻia kēia mau hopena i ke kanaka. Ke nānā nei kahi hoʻokolohua lapaʻau ʻāpana II inā hiki i ka benfotiamine ke kāpae i ka emi ʻana o ka cognitive i nā poʻe maʻi me ka maʻi naʻau.

3. Ka lanakila ʻana i ka hilinaʻi ʻana i ka waiʻona

Hoʻopili ʻia ka inu ʻana i ka waiʻona me ka hemahema nui o nā meaʻai koʻikoʻi a me nā huaora. Hōʻike ʻia ka nele o ka thiamine pili i ka waiʻona e nā maʻi neurological ma muli o ka nalowale holomua o ka mea keʻokeʻo waena a me ka peripheral. ʻOiai he mea nui ka hoʻololi ʻana i ka thiamine no nā poʻe maʻi me ka pōʻino o ka ʻōnaehana kūloko i hoʻokomo ʻia i ka waiʻona, ʻaʻole i hōʻoia maikaʻi ʻia ka benfotiamine i ka hele ʻana i loko o ka ʻōnaehana nerve waena mai ka ʻaoʻao.

4. Benfotiamine no ka puhi paka

ʻO ka puhi paka ke alakaʻi i ka endothelial dysfunction, kahi hanana mua i ka maʻi cardiovascular. Hoʻonui ʻia kēia e ke kaumaha oxidative a me ka mumū. Ma kahi noiʻi preclinical e pili ana i nā ʻiole, ua ʻike ʻia ka benfotiamine e pale aku i ka maʻi vascular induced nicotine. Ua hōʻike ʻia kahi hoʻokolohua i mālama ʻia i nā mea manawaleʻa olakino e hiki i ka mālama pōkole me ka benfotiamine ke hoʻihoʻi i kekahi hapa o ka hana macrovascular i nā mea puhi puhi olakino.

5. Ka pale ʻana i ka ʻōpū

Hōʻike ka ʻikepili mai nā noiʻi ʻana i ka ʻiole e hāʻawi ka benfotiamine i ka hana pale i ka membrane peritoneal a me ke koena o ke kīpē i ka peritoneal dialysis a me ka uremia. Wahi a kahi noiʻi i paʻi ʻia ma ka Journal of the American Society of Nephrology, ʻo ka hoʻohui ʻana o benfotiamine i loko o ka meaʻai e alakaʻi i ka hoʻonui ʻana i ka hana transketolase a me ka hoʻohaʻahaʻa ʻana i ka hōʻike ʻana o nā huahana hope glycation kiʻekiʻe a me kā lākou mea loaʻa.

ʻO kahi haʻawina na Ustuner et al. i paʻi ʻia ma ka Tissue and Cell i ʻike ʻia he kōkua ʻo benfotiamine supplement i ka attenuating antibiotic-induced nephrotoxicity ma o ka hoʻomaikaʻi ʻana i ke koʻikoʻi oxidative a me ka mumū o nā pūpū tubular renal.

6. Hiki i ka antitumor

Hōʻike nā haʻawina in vitro e hiki i ka benfotiamine ke hoʻopau i ka maʻi leukemia ma kahi ʻano i kapa ʻia ʻo ka make cell paraptosis. ʻO ka paraptosis kahi ʻano o ka make cell programmed e pili ana i ka cytoplasmic vacuole formation. Ua ʻike ʻia kahi noiʻi moʻomeheu cell a nā mea noiʻi o ke Kulanui ʻo Kanazawa ma Iapana he mea hoʻohiki ʻo benfotiamine no nā poʻe maʻi leukemia myeloid acute ʻaʻole i kūpono i ka chemotherapy maʻamau. Ua ʻike pū lākou ua hōʻike ʻo benfotiamine i ka hana synergistic me ka cytarabine, kahi mea hana chemotherapeutic, e hoʻopau i nā pūnaeau leukemia myeloid.

7. Nā waiwai antioxidant

ʻO Benfotiamine kekahi antioxidant ikaika me nā waiwai anti-inflammatory i hana ʻia ma o ka pale ʻana i ka prostaglandin a me ka leukotriene synthesis.